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8 articles|26 min total

Our fat is in the fire. Blazing like napalm in the morning, an unrelenting chain reaction of lipid oxidation keeps claiming victory after victory over our antioxidant defences, burning us into our old, doddery replicas. Can we stop the apocalypse, now?

A preface journey into the chemistry of lipid peroxidation and why antioxidants fail, through the deuterium-based answer, to health implications. Read in order or jump to any article, as a warm-up to reading the book.

The Problem| 3 min

1. Why this book? Because the chain reaction of lipid peroxidation is everywhere

From a BBQ party in Texas to Flemish painters studios. Why 'oil' and 'air' are the common topics in biology and art, and how oxygen plays a role in our demise.

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Aging Mechanism| 3 min

2. Chain reaction of lipid peroxidation plays a major role in aging and disease

Every cell in our body has elaborate barrier structures called lipid membranes. Learn how LPO targets them like falling dominoes.

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Why It Fails| 4 min

3. Antioxidants cannot stop the chain reaction of lipid peroxidation

Why traditional antioxidants fail to stop the exponential nature of the damage, while stray copper and iron can make it worse.

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The Solution| 5 min

4. Deuterium against the chain reaction of lipid peroxidation

How substituting Hydrogen with its heavier isotope Deuterium creates unbreakable bonds and stops the damage without changing the chemistry.

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Health Benefits| 4 min

5. D-PUFA against neurological, retinal and metabolic diseases

From Alzheimer's to Atherosclerosis: how D-PUFAs act as a common denominator in mitigating age-related decline.

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Inflammation| 3 min

6. D-PUFAs may help hold inflammation at bay

Why we don't want to stop inflammation altogether (like Aspirin does), but softly nudge it down by keeping pro-inflammatory eicosanoids in check.

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Definition| 2 min

7. D-PUFA are an unusual thing, and challenging to categorise

Neither drugs nor supplements. They are recognized as 'natural' building blocks, yet their action is strong. How should we classify them?

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Mechanism| 2 min

8. D-PUFA operate on physical, not chemical, principles

Why drugs often fail due to side effects and resistance, while D-PUFAs rely on reliable, predictable physical mechanisms.

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Want the full picture?

This article covers just one piece of the puzzle. The book connects all the dots: from the chemistry of aging to the deuterium approach.

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